• Western blot analysis of extracts of various cell lines, using PMVK antibody (STJ115805) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-PMVK antibody (1-192) (STJ115805)

SKU:
STJ115805

Shipping:
Free Shipping
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PMVK (1-192) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PMVK
Gene ID: 10654
Uniprot ID: PMVK_HUMAN
Immunogen Region: 1-192
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-192 of human PMVK (NP_006547.1).
Immunogen Sequence: MAPLGGAPRLVLLFSGKRKS GKDFVTEALQSRLGADVCAV LRLSGPLKEQYAQEHGLNFQ RLLDTSTYKEAFRKDMIRWG EEKRQADPGFFCRKIVEGIS QPIWLVSDTRRVSDIQWFRE AYGAVTQTVRVVALEQSRQQ RGWVFTPGVDDAESECGLDN FGDFDWVIENHGVEQRLEEQ LENLIEFIRSRL
Tissue Specificity Heart, liver, skeletal muscle, kidney, and pancreas. Lower level in brain, placenta and lung.
Function Catalyzes the reversible ATP-dependent phosphorylation of mevalonate 5-phosphate to produce mevalonate diphosphate and ADP, a key step in the mevalonic acid mediated biosynthesis of isopentenyl diphosphate and other polyisoprenoid metabolites.
Protein Name Phosphomevalonate Kinase
Pmkase
Hpmk
Database Links Reactome: R-HSA-191273
Reactome: R-HSA-2426168
Cellular Localisation Cytoplasm
Cytosol
Alternative Antibody Names Anti-Phosphomevalonate Kinase antibody
Anti-Pmkase antibody
Anti-Hpmk antibody
Anti-PMVK antibody
Anti-PMKI antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance