| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PMVK (1-192) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PMVK |
| Gene ID: |
10654 |
| Uniprot ID: |
PMVK_HUMAN |
| Immunogen Region: |
1-192 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-192 of human PMVK (NP_006547.1). |
| Immunogen Sequence: |
MAPLGGAPRLVLLFSGKRKS GKDFVTEALQSRLGADVCAV LRLSGPLKEQYAQEHGLNFQ RLLDTSTYKEAFRKDMIRWG EEKRQADPGFFCRKIVEGIS QPIWLVSDTRRVSDIQWFRE AYGAVTQTVRVVALEQSRQQ RGWVFTPGVDDAESECGLDN FGDFDWVIENHGVEQRLEEQ LENLIEFIRSRL |
| Tissue Specificity | Heart, liver, skeletal muscle, kidney, and pancreas. Lower level in brain, placenta and lung. |
| Function | Catalyzes the reversible ATP-dependent phosphorylation of mevalonate 5-phosphate to produce mevalonate diphosphate and ADP, a key step in the mevalonic acid mediated biosynthesis of isopentenyl diphosphate and other polyisoprenoid metabolites. |
| Protein Name | Phosphomevalonate KinasePmkaseHpmk |
| Database Links | Reactome: R-HSA-191273Reactome: R-HSA-2426168 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Phosphomevalonate Kinase antibodyAnti-Pmkase antibodyAnti-Hpmk antibodyAnti-PMVK antibodyAnti-PMKI antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
