| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PLEKHG4 |
| Gene ID: | 25894 |
| Uniprot ID: | PKHG4_HUMAN |
| Immunogen Region: | 710-1010 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 710-1010 of human PLEKHG4 (NP_001123199.1). |
| Immunogen Sequence: | GALPQASPTVPPPGSSDPRS LNRLQLVLAEMVATEREYVR ALEYTMENYFPELDRPDVPQ GLRGQRAHLFGNLEKLRDFH CHFFLRELEACTRHPPRVAY AFLRHRVQFGMYALYSKNKP RSDALMSSYGHTFFKDKQQA LGDHLDLASYLLKPIQRMGK YALLLQELARACGGPTQELS ALREAQSLVHFQLRHGNDLL AMDAIQGCDVNLKEQGQLVR QDEFVVRTGRHKSVRRIFL |
| Tissue Specificity | Expressed in kidney, Leydig cells in the testis, epithelial cells in the prostate gland and Langerhans islet in the pancreas. Isoform 1 and isoform 3 are strongly expressed in Purkinje cells and to a lower extent in other neurons (at protein level). Widely expressed at low levels. More strongly expressed in testis and pancreas. |
| Function | Possible role in intracellular signaling and cytoskeleton dynamics at the Golgi. |
| Protein Name | Puratrophin-1Pleckstrin Homology Domain-Containing Family G Member 4Ph Domain-Containing Family G Member 4Purkinje Cell Atrophy-Associated Protein 1 |
| Database Links | Reactome: R-HSA-8980692Reactome: R-HSA-9013148Reactome: R-HSA-9013149 |
| Alternative Antibody Names | Anti-Puratrophin-1 antibodyAnti-Pleckstrin Homology Domain-Containing Family G Member 4 antibodyAnti-Ph Domain-Containing Family G Member 4 antibodyAnti-Purkinje Cell Atrophy-Associated Protein 1 antibodyAnti-PLEKHG4 antibodyAnti-PRTPHN1 antibody |
Information sourced from Uniprot.org