||Human, Rat, Mouse, Monkey, Canine
||FOR RESEARCH USE ONLY (RUO).
||Goat polyclonal antibody anti-Protein disulfide-isomerase A6 (220aa C-Term) is suitable for use in Western Blot research applications.
||PBS, 20% Glycerol and 0.05% Sodium Azide.
||This antibody is epitope-affinity purified from goat antiserum.
||For continuous use, store at 2-8 C for one-two days. For extended storage, store in-20 C freezer. Working dilution samples should be discarded if not used within 12 hours.
||Detects endogenous levels of PDIA6 by Western blot.
||Recombinant peptide derived from within residues 220 aa to the C-terminus of human PDIA6 produced in E. coli.
| Tissue Specificity || Expressed in platelets (at protein level). |
| Function || May function as a chaperone that inhibits aggregation of misfolded proteins. Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling. May also regulate the UPR via the EIF2AK3 UPR sensor. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin. |
| Protein Name || Protein Disulfide-Isomerase A6Endoplasmic Reticulum Protein 5Er Protein 5Erp5Protein Disulfide Isomerase P5Thioredoxin Domain-Containing Protein 7 |
| Database Links || Reactome: R-HSA-381038Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation || Endoplasmic Reticulum LumenCell MembraneMelanosomeIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Antibody Names || Anti-Protein Disulfide-Isomerase A6 antibodyAnti-Endoplasmic Reticulum Protein 5 antibodyAnti-Er Protein 5 antibodyAnti-Erp5 antibodyAnti-Protein Disulfide Isomerase P5 antibodyAnti-Thioredoxin Domain-Containing Protein 7 antibodyAnti-PDIA6 antibodyAnti-ERP5 antibodyAnti-P5 antibodyAnti-TXNDC7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance