| Host: |
Rabbit |
| Applications: |
ELISA/IHC/IP/WB |
| Reactivity: |
Human/Monkey/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PDCD1LG2 (115-165) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Biotin |
| Isotype: |
IgG |
| Purification: |
Affinity Purified |
| Concentration: |
0.5 µg/µl |
| Dilution Range: |
WB: 1:500ELISA: 1:10, 000IP: 1:150IHC: 1:50-1:150 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
PDCD1LG2 |
| Gene ID: |
80380 |
| Uniprot ID: |
PD1L2_HUMAN |
| Immunogen Region: |
115-165 |
| Immunogen: |
Synthetic peptide taken within amino acid region 115-165 on human Programmed cell death 1 ligand 2 protein. |
| Tissue Specificity | Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus. |
| Function | Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. |
| Protein Name | Programmed Cell Death 1 Ligand 2Pd-1 Ligand 2Pd-L2Pdcd1 Ligand 2Programmed Death Ligand 2Butyrophilin B7-DcB7-DcCd Antigen Cd273 |
| Database Links | Reactome: R-HSA-389948 |
| Cellular Localisation | Isoform 3: SecretedIsoform 2: Endomembrane SystemSingle-Pass Type I Membrane ProteinIsoform 1: Cell Membrane |
| Alternative Antibody Names | Anti-Programmed Cell Death 1 Ligand 2 antibodyAnti-Pd-1 Ligand 2 antibodyAnti-Pd-L2 antibodyAnti-Pdcd1 Ligand 2 antibodyAnti-Programmed Death Ligand 2 antibodyAnti-Butyrophilin B7-Dc antibodyAnti-B7-Dc antibodyAnti-Cd Antigen Cd273 antibodyAnti-PDCD1LG2 antibodyAnti-B7DC antibodyAnti-CD273 antibodyAnti-PDCD1L2 antibodyAnti-PDL2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
