| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NPY2R |
| Gene ID: | 4887 |
| Uniprot ID: | NPY2R_HUMAN |
| Immunogen Region: | C-Term |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human NPY2R (NP_000901.1). |
| Immunogen Sequence: | LKEYKLIFTVFHIIAMCSTF ANPLLYGWMNSNYRKAFLSA FRCEQRLDAIHSEVSVTFKA KKNLEVRKNSGPNDSFTEAT NV |
| Tissue Specificity | High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra. |
| Function | Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > Ile-31, Gln-34 PP > Leu-31, Pro-34 NPY > PP, Pro-34 PYY and NPY free acid. |
| Protein Name | Neuropeptide Y Receptor Type 2Npy2-RNpy-Y2 ReceptorY2 Receptor |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Neuropeptide Y Receptor Type 2 antibodyAnti-Npy2-R antibodyAnti-Npy-Y2 Receptor antibodyAnti-Y2 Receptor antibodyAnti-NPY2R antibody |
Information sourced from Uniprot.org