| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NFYA |
| Gene ID: | 4800 |
| Uniprot ID: | NFYA_HUMAN |
| Immunogen Region: | 1-318 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-318 of human NFYA (NP_068351.1). |
| Immunogen Sequence: | MEQYTANSNSSTEQIVVQAG QIQQQVQGQPLMVQVSGGQL ITSTGQPIMVQAVPGGQGQT IMQVPVSGTQGLQQIQLVPP GQIQIQGGQAVQVQGQQGQT QQIIIQQPQTAVTAGQTQTQ QQIAVQGQQVAQTAEGQTIV YQPVNADGTILQQVTVPVSG MITIPAASLAGAQIVQTGAN TNTTSSGQGTVTVTLPVAGN VVNSGGMVMMVPGAGSVPAI QRIPLPGAEMLEEEPLYVN |
| Function | Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. NF-YA positively regulates the transcription of the core clock component BMAL1. |
| Protein Name | Nuclear Transcription Factor Y Subunit Alpha Caat Box Dna-Binding Protein Subunit A Nuclear Transcription Factor Y Subunit A Nf-Ya |
| Database Links | Reactome: R-HSA-1989781 Reactome: R-HSA-2426168 Reactome: R-HSA-380994 Reactome: R-HSA-381183 Reactome: R-HSA-9614657 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Nuclear Transcription Factor Y Subunit Alpha antibody Anti-Caat Box Dna-Binding Protein Subunit A antibody Anti-Nuclear Transcription Factor Y Subunit A antibody Anti-Nf-Ya antibody Anti-NFYA antibody |
Information sourced from Uniprot.org