| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NFIB |
| Gene ID: | 4781 |
| Uniprot ID: | NFIB_HUMAN |
| Immunogen Region: | C-Term |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human NFIB (NP_005587.2). |
| Immunogen Sequence: | SRTWHERDQDMSSPTTMKKP EKPLFSSASPQDSSPRLSTF PQHHHPGIPGVAHSVISTRT PPPPSPLPFPTQAILPPAPS SYFSHPTIRYPPHLNPQDTL KNYVPSYDPSSPQTSQSWYL G |
| Function | Transcriptional activator of GFAP, essential for proper brain development. Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. |
| Protein Name | Nuclear Factor 1 B-TypeNf1-BNuclear Factor 1/BCcaat-Box-Binding Transcription FactorCtfNuclear Factor I/BNf-I/BNfi-BTggca-Binding Protein |
| Database Links | Reactome: R-HSA-73980Reactome: R-HSA-749476 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Nuclear Factor 1 B-Type antibodyAnti-Nf1-B antibodyAnti-Nuclear Factor 1/B antibodyAnti-Ccaat-Box-Binding Transcription Factor antibodyAnti-Ctf antibodyAnti-Nuclear Factor I/B antibodyAnti-Nf-I/B antibodyAnti-Nfi-B antibodyAnti-Tggca-Binding Protein antibodyAnti-NFIB antibody |
Information sourced from Uniprot.org