| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-N-terminal EF-hand calcium-binding protein 3 (321-370 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:40000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NECAB3 |
| Gene ID: | 63941 |
| Uniprot ID: | NECA3_HUMAN |
| Immunogen Region: | 321-370 aa |
| Specificity: | APBA2BP Polyclonal Antibody detects endogenous levels of APBA2BP protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human NECAB3 at the amino acid range 321-370 |
| Post Translational Modifications | Phosphorylated by NEK2. |
| Function | Inhibits the interaction of APBA2 with amyloid-beta precursor protein (APP), and hence allows formation of amyloid-beta. May enhance the activity of HIF1A and thus promote glycolysis under normoxic conditions.the function requires its ABM domain and may implicate the stabilization of the interaction between HIF1AN and APBA3. |
| Protein Name | N-Terminal Ef-Hand Calcium-Binding Protein 3Amyloid-Beta A4 Protein-Binding Family A Member 2-Binding ProteinNek2-Interacting Protein 1Neuronal Calcium-Binding Protein 3X11l-Binding Protein 51 |
| Cellular Localisation | Golgi Apparatus |
| Alternative Antibody Names | Anti-N-Terminal Ef-Hand Calcium-Binding Protein 3 antibodyAnti-Amyloid-Beta A4 Protein-Binding Family A Member 2-Binding Protein antibodyAnti-Nek2-Interacting Protein 1 antibodyAnti-Neuronal Calcium-Binding Protein 3 antibodyAnti-X11l-Binding Protein 51 antibodyAnti-NECAB3 antibodyAnti-APBA2BP antibodyAnti-NIP1 antibodyAnti-SYTIP2 antibodyAnti-XB51 antibody |
Information sourced from Uniprot.org