| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NCOA5 |
| Gene ID: | 57727 |
| Uniprot ID: | NCOA5_HUMAN |
| Immunogen Region: | 240-380 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 240-380 of human NCOA5 (NP_066018.1). |
| Immunogen Sequence: | QALEDVSRGGSPFAIVITQQ HQIHRSCTVNIMFGTPQEHR NMPQADAMVLVARNYERYKN ECREKEREEIARQAAKMADE AILQERERGGPEEGVRGGHP PAIQSLINLLADNRYLTAEE TDKIINYLRERKERLMRSST D |
| Tissue Specificity | Widely expressed. |
| Function | Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. Involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC in response to 17-beta-estradiol (E2). |
| Protein Name | Nuclear Receptor Coactivator 5Ncoa-5Coactivator Independent Of Af-2Cia |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Nuclear Receptor Coactivator 5 antibodyAnti-Ncoa-5 antibodyAnti-Coactivator Independent Of Af-2 antibodyAnti-Cia antibodyAnti-NCOA5 antibodyAnti-KIAA1637 antibody |
Information sourced from Uniprot.org