Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-NCOA5 (240-380) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
NCOA5 |
Gene ID: |
57727 |
Uniprot ID: |
NCOA5_HUMAN |
Immunogen Region: |
240-380 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 240-380 of human NCOA5 (NP_066018.1). |
Immunogen Sequence: |
QALEDVSRGGSPFAIVITQQ HQIHRSCTVNIMFGTPQEHR NMPQADAMVLVARNYERYKN ECREKEREEIARQAAKMADE AILQERERGGPEEGVRGGHP PAIQSLINLLADNRYLTAEE TDKIINYLRERKERLMRSST D |
Tissue Specificity | Widely expressed. |
Function | Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. Involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC in response to 17-beta-estradiol (E2). |
Protein Name | Nuclear Receptor Coactivator 5Ncoa-5Coactivator Independent Of Af-2Cia |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Nuclear Receptor Coactivator 5 antibodyAnti-Ncoa-5 antibodyAnti-Coactivator Independent Of Af-2 antibodyAnti-Cia antibodyAnti-NCOA5 antibodyAnti-KIAA1637 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance