Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Gene Symbol: | NCAN |
Gene ID: | 1463 |
Uniprot ID: | NCAN_HUMAN |
Immunogen Region: | 150-357 aa |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 150-357 of human NCAN (NP_004377.2). |
Tissue Specificity | Detected in cerebrospinal fluid (at protein level). Brain. |
Post Translational Modifications | O-glycosylated.contains chondroitin sulfate. |
Function | May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM). Chondroitin sulfate proteoglycan.binds to hyaluronic acid. |
Protein Name | Neurocan Core ProteinChondroitin Sulfate Proteoglycan 3 |
Database Links | Reactome: R-HSA-1971475Reactome: R-HSA-2022870Reactome: R-HSA-2022923Reactome: R-HSA-2024101Reactome: R-HSA-3000178Reactome: R-HSA-3560783Reactome: R-HSA-3560801Reactome: R-HSA-3595172Reactome: R-HSA-3595174Reactome: R-HSA-3595177Reactome: R-HSA-373760Reactome: R-HSA-419037Reactome: R-HSA-4420332 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Neurocan Core Protein antibodyAnti-Chondroitin Sulfate Proteoglycan 3 antibodyAnti-NCAN antibodyAnti-CSPG3 antibodyAnti-NEUR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance