| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MYLK2 |
| Gene ID: | 85366 |
| Uniprot ID: | MYLK2_HUMAN |
| Immunogen Region: | 1-90 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human MYLK2 (NP_149109.1). |
| Immunogen Sequence: | MATENGAVELGIQNPSTDKA PKGPTGERPLAAGKDPGPPD PKKAPDPPTLKKDAKAPASE KGDGTLAQPSTSSQGPKGEG DRGGGPAEGS |
| Tissue Specificity | Heart and skeletal muscles. Increased expression in the apical tissue compared to the interventricular septal tissue. |
| Function | Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N-terminus of a myosin light chain. |
| Protein Name | Myosin Light Chain Kinase 2 - Skeletal/Cardiac Muscle Mlck2 |
| Cellular Localisation | Cytoplasm Colocalizes With Phosphorylated Myosin Light Chain (Rlcp) At Filaments Of The Myofibrils |
| Alternative Antibody Names | Anti-Myosin Light Chain Kinase 2 - Skeletal/Cardiac Muscle antibody Anti-Mlck2 antibody Anti-MYLK2 antibody |
Information sourced from Uniprot.org