| Tissue Specificity | Expressed in adrenal cortex, testis, breast, thyroid, lymph node, ovary and fat. Expressed in adipose tissues. |
| Function | Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R). Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin (ACTH). May be involved in the intracellular trafficking pathways in adipocyte cells. |
| Protein Name | Melanocortin-2 Receptor Accessory ProteinB27Fat Cell-Specific Low Molecular Weight ProteinFat Tissue-Specific Low Mw Protein |
| Cellular Localisation | Cell MembraneSingle-Pass Membrane ProteinEndoplasmic Reticulum MembraneThe Formation Of Antiparallel Homo- And Heterodimers Suggest That N- And C-Terminus Can Both Localize In The Cytoplasmic And Extracellular PartsDepending On The ContextUpon Insulin StimulationIt Is Redistributed Into Spotty Structures Throughout The Cytoplasm |
| Alternative Antibody Names | Anti-Melanocortin-2 Receptor Accessory Protein antibodyAnti-B27 antibodyAnti-Fat Cell-Specific Low Molecular Weight Protein antibodyAnti-Fat Tissue-Specific Low Mw Protein antibodyAnti-MRAP antibodyAnti-C21orf61 antibodyAnti-FALP antibody |
Information sourced from Uniprot.org
