| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MMEL1 (350-450) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MMEL1 |
| Gene ID: |
79258 |
| Uniprot ID: |
MMEL1_HUMAN |
| Immunogen Region: |
350-450 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human MMEL1 (NP_258428.2). |
| Immunogen Sequence: |
NWTLFIQTVLSSVKIKLLPD EEVVVYGIPYLQNLENIIDT YSARTIQNYLVWRLVLDRIG SLSQRFKDTRVNYRKALFGT MVEEVRWRECVGYVNSNMEN A |
| Tissue Specificity | Predominantly expressed in testis. Weakly expressed in brain, kidney and heart. |
| Post Translational Modifications | N-glycosylated. |
| Function | Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificity with MME and cleaves peptides at the same amide bond. |
| Protein Name | Membrane Metallo-Endopeptidase-Like 1Membrane Metallo-Endopeptidase-Like 2Nep2(MNeprilysin IiNepiiNeprilysin-2Nep2Nl2 Cleaved Into - Membrane Metallo-Endopeptidase-Like 1 - Soluble FormNeprilysin-2 SecretedNep2(S |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane ProteinSecretedA Secreted Form Produced By Proteolytic Cleavage Also Exists |
| Alternative Antibody Names | Anti-Membrane Metallo-Endopeptidase-Like 1 antibodyAnti-Membrane Metallo-Endopeptidase-Like 2 antibodyAnti-Nep2(M antibodyAnti-Neprilysin Ii antibodyAnti-Nepii antibodyAnti-Neprilysin-2 antibodyAnti-Nep2 antibodyAnti-Nl2 Cleaved Into - Membrane Metallo-Endopeptidase-Like 1 - Soluble Form antibodyAnti-Neprilysin-2 Secreted antibodyAnti-Nep2(S antibodyAnti-MMEL1 antibodyAnti-MELL1 antibodyAnti-MMEL2 antibodyAnti-NEP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
