| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | MLLT11 |
| Gene ID: | 10962 |
| Uniprot ID: | AF1Q_HUMAN |
| Immunogen Region: | 1-90 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human MLLT11 (NP_006809.1). |
| Immunogen Sequence: | MRDPVSSQYSSFLFWRMPIP ELDLSELEGLGLSDTATYKV KDSSVGKMIGQATAADQEKN PEGDGLLEYSTFNFWRAPIA SIHSFELDLL |
| Tissue Specificity | Expressed in myoepithelial cells of normal breast tissue (at protein level). Highly expressed in thymus. Expressed in colon, small intestine, prostate and ovary. Not detected in peripheral blood lymphocytes and spleen. |
| Post Translational Modifications | Ubiquitinated, leading to degradation. |
| Function | Cofactor for the transcription factor TCF7. Involved in regulation of lymphoid development by driving multipotent hematopoietic progenitor cells towards a T cell fate. |
| Protein Name | Protein Af1q |
| Cellular Localisation | NucleusCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeContinuous Nuclear Export Is Followed By Degradation |
| Alternative Antibody Names | Anti-Protein Af1q antibodyAnti-MLLT11 antibodyAnti-AF1Q antibody |
Information sourced from Uniprot.org