| Post Translational Modifications | Phosphorylated on serine and threonine residues. |
| Function | Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination. |
| Protein Name | E3 Ubiquitin-Protein Ligase Midline-1MidinPutative Transcription Factor XprfRing Finger Protein 59Ring Finger Protein Midline-1Ring-Type E3 Ubiquitin Transferase Midline-1Tripartite Motif-Containing Protein 18 |
| Database Links | Reactome: R-HSA-877300 |
| Cellular Localisation | CytoplasmCytoskeletonSpindleMicrotubule-AssociatedIt Is Associated With Microtubules Throughout The Cell CycleCo-Localizing With Cytoplasmic Fibers In Interphase And With The Mitotic Spindle And Midbodies During Mitosis And Cytokinesis |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Midline-1 antibodyAnti-Midin antibodyAnti-Putative Transcription Factor Xprf antibodyAnti-Ring Finger Protein 59 antibodyAnti-Ring Finger Protein Midline-1 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Midline-1 antibodyAnti-Tripartite Motif-Containing Protein 18 antibodyAnti-MID1 antibodyAnti-FXY antibodyAnti-RNF59 antibodyAnti-TRIM18 antibodyAnti-XPRF antibody |
Information sourced from Uniprot.org
