• Western blot analysis of lysates from Rat brain, using MBIP Rabbit polyclonal antibody (STJ119749) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 15s.

Anti-MBIP antibody (1-344) (STJ119749)

SKU:
STJ119749

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MBIP (1-344) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MBIP
Gene ID: 51562
Uniprot ID: MBIP1_HUMAN
Immunogen Region: 1-344
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-344 of human MBIP (NP_057670.2).
Immunogen Sequence: MAAATELNRPSSGDRNLERR CRPNLSREVLYEIFRSLHTL VGQLDLRDDVVKITIDWNKL QSLSAFQPALLFSALEQHIL YLQPFLAKLQSPIKEENTTA VEEIGRTEMGNKNEVNDKFS IGDLQEEEKHKESDLRDVKK TQIHFDPEVVQIKAGKAEID RRISAFIERKQAEINENNVR EFCNVIDCNQENSCARTDAI FTPYPGFKSHVKVSRVVNTY GPQTRPEGIPGSGHKPNSM
Tissue Specificity Ubiquitous. High expression seen in the heart and lung.
Function Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Protein Name Map3k12-Binding Inhibitory Protein 1
Mapk Upstream Kinase-Binding Inhibitory Protein
Muk-Binding Inhibitory Protein
Database Links Reactome: R-HSA-3214847
Reactome: R-HSA-9772755
Cellular Localisation Nucleus
Cytoplasm
Shows A Cytoplasmic Localization When Coexpressed With Map3k12
Alternative Antibody Names Anti-Map3k12-Binding Inhibitory Protein 1 antibody
Anti-Mapk Upstream Kinase-Binding Inhibitory Protein antibody
Anti-Muk-Binding Inhibitory Protein antibody
Anti-MBIP antibody
Anti-BM-015 antibody

Information sourced from Uniprot.org

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