| Function | Seems to act as a scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in receptor-mediated clathrin-dependent endocytosis which is required for ciliogenesis. |
| Protein Name | Membrane-Associated Guanylate Kinase - Ww And Pdz Domain-Containing Protein 2Atrophin-1-Interacting Protein 1Aip-1Atrophin-1-Interacting Protein AMembrane-Associated Guanylate Kinase Inverted 2Magi-2 |
| Database Links | Reactome: R-HSA-373753 |
| Cellular Localisation | CytoplasmLate EndosomeSynapseSynaptosomeCell MembranePeripheral Membrane ProteinCytoskeletonMicrotubule Organizing CenterCentrosomeCell ProjectionCiliumCentriolePhotoreceptor Inner SegmentPhotoreceptor Outer SegmentLocalized Diffusely In The Cytoplasm Before Nerve Growth Factor (Ngf) StimulationRecruited To Late Endosomes After Ngf StimulationMembrane-Associated In Synaptosomes |
| Alternative Antibody Names | Anti-Membrane-Associated Guanylate Kinase - Ww And Pdz Domain-Containing Protein 2 antibodyAnti-Atrophin-1-Interacting Protein 1 antibodyAnti-Aip-1 antibodyAnti-Atrophin-1-Interacting Protein A antibodyAnti-Membrane-Associated Guanylate Kinase Inverted 2 antibodyAnti-Magi-2 antibodyAnti-MAGI2 antibodyAnti-ACVRINP1 antibodyAnti-AIP1 antibodyAnti-KIAA0705 antibody |
Information sourced from Uniprot.org
