| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LYPD1 |
| Gene ID: | 116372 |
| Uniprot ID: | LYPD1_HUMAN |
| Immunogen Region: | 21-141 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-141 of human LYPD1 (NP_653187.3). |
| Immunogen Sequence: | LQIQCYQCEEFQLNNDCSSP EFIVNCTVNVQDMCQKEVME QSAGIMYRKSCASSAACLIA SAGYQSFCSPGKLNSVCISC CNTPLCNGPRPKKRGSSASA LRPGLRTTILFLKLALFSAH C |
| Function | Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro increases receptor desensitization and decreases affinity for ACh of alpha-4:beta-2-containing nAChRs. May play a role in the intracellular trafficking of alpha-4:beta-2 and alpha-7-containing nAChRs and may inhibit their expression at the cell surface. May be involved in the control of anxiety. |
| Protein Name | Ly6/Plaur Domain-Containing Protein 1Putative Hela Tumor SuppressorPhts |
| Database Links | Reactome: R-HSA-163125 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Ly6/Plaur Domain-Containing Protein 1 antibodyAnti-Putative Hela Tumor Suppressor antibodyAnti-Phts antibodyAnti-LYPD1 antibodyAnti-Lynx2 antibodyAnti-LYPDC1 antibodyAnti-PSEC0181 antibodyAnti-UNQ3079 antibodyAnti-PRO9917 antibody |
Information sourced from Uniprot.org