Host: | Mouse |
Applications: | FC/IF/IHC |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-Liver antigen is suitable for use in Flow Cytometry, Immunofluorescence and Immunohistochemistry research applications. |
Clonality : | Monoclonal |
Clone ID : | EP-2 |
Conjugation: | Unconjugated |
Isotype: | IgG2bk |
Formulation: | PBS with 0.02% Sodium Azide. |
Purification: | Affinity purified from tissue culture. |
Concentration: | Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
Dilution Range: | Flow cytometry (0, 5-1, 0 µg/million cells in 0, 1 ml). Immunofluorescence (0, 5-1, 0 µg/ml). Immunohistology (1-2 µg/ml for 30 min at RT; an appropriate antigen retrieval method for staining of formalin-fixed tissues has not been established to date |
Storage Instruction: | Store for up to 1 year at 2-8°C upon receipt. |
Gene Symbol: | CDC42EP2 |
Gene ID: | 10435 |
Uniprot ID: | BORG1_HUMAN |
Immunogen: | A BALB/c mouse was immunized with HEB-3B human hepatocarcinoma cells. Fusion partner: NS-1. |
Tissue Specificity | Highly expressed in the heart. Weakly expressed in the pancreas and liver. |
Function | Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner. |
Protein Name | Cdc42 Effector Protein 2Binder Of Rho Gtpases 1 |
Database Links | Reactome: R-HSA-5687128Reactome: R-HSA-9013148Reactome: R-HSA-9013406 |
Cellular Localisation | Endomembrane SystemPeripheral Membrane ProteinCytoplasmCytoskeleton |
Alternative Antibody Names | Anti-Cdc42 Effector Protein 2 antibodyAnti-Binder Of Rho Gtpases 1 antibodyAnti-CDC42EP2 antibodyAnti-BORG1 antibodyAnti-CEP2 antibody |
Information sourced from Uniprot.org