| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KLF7 |
| Gene ID: | 8609 |
| Uniprot ID: | KLF7_HUMAN |
| Immunogen Region: | 51-230 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 51-230 of human KLF7 (NP_001257871.1). |
| Immunogen Sequence: | SETFGEDLDCFLHASPPPCI EESFRRLDPLLLPVEAAICE KSSAVDILLSRDKLLSETCL SLQPASSSLDSYTAVNQAQL NAVTSLTPPSSPELSRHLVK TSQTLSAVDGTVTLKLVAKK AALSSVKVRSLISAHGRDVS GVLHEAMSSRGTTGNTQVQS PSNATTATGVFPGLTILPST |
| Tissue Specificity | Widely expressed. |
| Function | Transcriptional factor. Plays a critical role in neuronal morphogenesis and survival of sensory neurons. Represses the corneal epithelium differentiation. Acts also as a metabolic regulator, by modulating insulin sensitivity in pancreatic beta cells and skeletal muscle cells. Inhibits transcriptional inducers of adipogenesis and has a repressive role in the expression of several adipokines, including leptin. |
| Protein Name | Krueppel-Like Factor 7Ubiquitous Krueppel-Like Factor |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Krueppel-Like Factor 7 antibodyAnti-Ubiquitous Krueppel-Like Factor antibodyAnti-KLF7 antibodyAnti-UKLF antibody |
Information sourced from Uniprot.org