| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-KIF18A (599-898) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KIF18A |
| Gene ID: |
81930 |
| Uniprot ID: |
KI18A_HUMAN |
| Immunogen Region: |
599-898 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 599-898 of human KIF18A (NP_112494.3). |
| Immunogen Sequence: |
SDFKEIEHLVERKKVVVWAD QTAEQPKQNDLPGISVLMTF PQLGPVQPIPCCSSSGGTNL VKIPTEKRTRRKLMPSPLKG QHTLKSPPSQSVQLNDSLSK ELQPIVYTPEDCRKAFQNPS TVTLMKPSSFTTSFQAISSN INSDNCLKMLCEVAIPHNRR KECGQEDLDSTFTICEDIKS SKCKLPEQESLPNDNKDILQ RLDPSSFSTKHSMPVPSMVP SYMAMTTAAKRKRKLTSST |
| Post Translational Modifications | Glycosylated. Ubiquitinated. |
| Function | Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression. |
| Protein Name | Kinesin-Like Protein Kif18aMarrow Stromal Kif18aMs-Kif18a |
| Database Links | Reactome: R-HSA-141444Reactome: R-HSA-2132295Reactome: R-HSA-2467813Reactome: R-HSA-2500257Reactome: R-HSA-5663220Reactome: R-HSA-6811434Reactome: R-HSA-68877Reactome: R-HSA-9648025Reactome: R-HSA-983189 |
| Cellular Localisation | Cell ProjectionRuffleCytoplasmNucleusCytoskeletonMicrotubule Organizing CenterCentrosome |
| Alternative Antibody Names | Anti-Kinesin-Like Protein Kif18a antibodyAnti-Marrow Stromal Kif18a antibodyAnti-Ms-Kif18a antibodyAnti-KIF18A antibodyAnti-OK antibodyAnti-SW-cl.108 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
