| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KCTD12 |
| Gene ID: | 115207 |
| Uniprot ID: | KCD12_HUMAN |
| Immunogen Region: | 196-325 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 196-325 of human KCTD12 (NP_612453.1). |
| Immunogen Sequence: | TPSQSLDGSRRSGYITIGYR GSYTIGRDAQADAKFRRVAR ITVCGKTSLAKEVFGDTLNE SRDPDRPPERYTSRYYLKFN FLEQAFDKLSESGFHMVACS STGTCAFASSTDQSEDKIWT SYTEYVFCRE |
| Tissue Specificity | Present in a variety of fetal organs, with highest expression levels in the cochlea and brain and, in stark contrast, is detected only at extremely low levels in adult organs, such as brain and lung. |
| Function | Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization. |
| Protein Name | Btb/Poz Domain-Containing Protein Kctd12PfetinPredominantly Fetal Expressed T1 Domain |
| Cellular Localisation | Presynaptic Cell MembranePostsynaptic Cell Membrane |
| Alternative Antibody Names | Anti-Btb/Poz Domain-Containing Protein Kctd12 antibodyAnti-Pfetin antibodyAnti-Predominantly Fetal Expressed T1 Domain antibodyAnti-KCTD12 antibodyAnti-C13orf2 antibodyAnti-KIAA1778 antibodyAnti-PFET1 antibody |
Information sourced from Uniprot.org