| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KCNE4 |
| Gene ID: |
23704 |
| Uniprot ID: |
KCNE4_HUMAN |
| Immunogen Region: |
108-221 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 108-221 of human KCNE4 (NP_542402.3). |
| Immunogen Sequence: |
YMKSKRREKKSSLLLLYKDE ERLWGEAMKPLPVVSGLRSV QVPLMLNMLQESVAPALSCT LCSMEGDSVSSESSSPDVHL TIQEEGADDELEETSETPLN ESSEGSSENIHQNS |
| Tissue Specificity | Predominantly expressed in embryo and adult uterus. Low expression found in kidney, small intestine, lung and heart. Isoform 1: Detected in kidney, thymus, and uterus (at protein level). |
| Function | Ancillary protein that functions as a regulatory subunit of the voltage-gated potassium (Kv) channel complex composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunits. KCNE4 beta subunit modulates the gating kinetics and enhances stability of the channel complex. Associates with KCNQ1/KVLTQ1 alpha subunit to inhibit potassium currents. Isoform 2: May inhibit KCNQ4-mediated potassium currents. |
| Protein Name | Potassium Voltage-Gated Channel Subfamily E Member 4Mink-Related Peptide 3Mirp3Minimum Potassium Ion Channel-Related Peptide 3Potassium Channel Subunit Beta Mirp3 |
| Database Links | Reactome: R-HSA-5576890Reactome: R-HSA-5576893 |
| Cellular Localisation | MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Potassium Voltage-Gated Channel Subfamily E Member 4 antibodyAnti-Mink-Related Peptide 3 antibodyAnti-Mirp3 antibodyAnti-Minimum Potassium Ion Channel-Related Peptide 3 antibodyAnti-Potassium Channel Subunit Beta Mirp3 antibodyAnti-KCNE4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
