• Western blot analysis of extracts of various cell lines, using KANSL1 antibody (STJ112653) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-KANSL1 antibody (806-1105) (STJ112653)

SKU:
STJ112653

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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KANSL1
Gene ID: 284058
Uniprot ID: KANL1_HUMAN
Immunogen Region: 806-1105
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 806-1105 of human KANSL1 (NP_056258.1).
Immunogen Sequence: SSSSYLAATHHPPHSPLVRQ LSTSSDSPAPASSSSQVTAS TSQQPVRRRRGESSFDINNI VIPMSVAATTRVEKLQYKEI LTPSWREVDLQSLKGSPDEE NEEIEDLSDAAFAALHAKCE EMERARWLWTTSVPPQRRGS RSYRSSDGRTTPQLGSANPS TPQPASPDVSSSHSLSEYSH GQSPRSPISPELHSAPLTPV ARDTPRHLASEDTRCSTPEL GLDEQSVQPWERRTFPLAH
Tissue Specificity Expressed in the brain.
Function Non-catalytic component of the NSL histone acetyltransferase complex, a multiprotein complex that mediates histone H4 acetylation at 'Lys-5'- and 'Lys-8' (H4K5ac and H4K8ac) at transcription start sites and promotes transcription initiation. The NSL complex also acts as a regulator of gene expression in mitochondria.
Protein Name Kat8 Regulatory Nsl Complex Subunit 1
Mll1/Mll Complex Subunit Kansl1
Msl1 Homolog 1
Hmsl1v1
Nsl Complex Protein Nsl1
Non-Specific Lethal 1 Homolog
Database Links Reactome: R-HSA-3214847
Reactome: R-HSA-9772755
Cellular Localisation Nucleus
Chromosome
Centromere
Kinetochore
Mitochondrion
Alternative Antibody Names Anti-Kat8 Regulatory Nsl Complex Subunit 1 antibody
Anti-Mll1/Mll Complex Subunit Kansl1 antibody
Anti-Msl1 Homolog 1 antibody
Anti-Hmsl1v1 antibody
Anti-Nsl Complex Protein Nsl1 antibody
Anti-Non-Specific Lethal 1 Homolog antibody
Anti-KANSL1 antibody
Anti-CENP-36 antibody
Anti-KIAA1267 antibody
Anti-MSL1V1 antibody
Anti-NSL1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance