| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KANSL1 |
| Gene ID: | 284058 |
| Uniprot ID: | KANL1_HUMAN |
| Immunogen Region: | 806-1105 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 806-1105 of human KANSL1 (NP_056258.1). |
| Immunogen Sequence: | SSSSYLAATHHPPHSPLVRQ LSTSSDSPAPASSSSQVTAS TSQQPVRRRRGESSFDINNI VIPMSVAATTRVEKLQYKEI LTPSWREVDLQSLKGSPDEE NEEIEDLSDAAFAALHAKCE EMERARWLWTTSVPPQRRGS RSYRSSDGRTTPQLGSANPS TPQPASPDVSSSHSLSEYSH GQSPRSPISPELHSAPLTPV ARDTPRHLASEDTRCSTPEL GLDEQSVQPWERRTFPLAH |
| Tissue Specificity | Expressed in the brain. |
| Function | Non-catalytic component of the NSL histone acetyltransferase complex, a multiprotein complex that mediates histone H4 acetylation at 'Lys-5'- and 'Lys-8' (H4K5ac and H4K8ac) at transcription start sites and promotes transcription initiation. The NSL complex also acts as a regulator of gene expression in mitochondria. |
| Protein Name | Kat8 Regulatory Nsl Complex Subunit 1Mll1/Mll Complex Subunit Kansl1Msl1 Homolog 1Hmsl1v1Nsl Complex Protein Nsl1Non-Specific Lethal 1 Homolog |
| Database Links | Reactome: R-HSA-3214847Reactome: R-HSA-9772755 |
| Cellular Localisation | NucleusChromosomeCentromereKinetochoreMitochondrion |
| Alternative Antibody Names | Anti-Kat8 Regulatory Nsl Complex Subunit 1 antibodyAnti-Mll1/Mll Complex Subunit Kansl1 antibodyAnti-Msl1 Homolog 1 antibodyAnti-Hmsl1v1 antibodyAnti-Nsl Complex Protein Nsl1 antibodyAnti-Non-Specific Lethal 1 Homolog antibodyAnti-KANSL1 antibodyAnti-CENP-36 antibodyAnti-KIAA1267 antibodyAnti-MSL1V1 antibodyAnti-NSL1 antibody |
Information sourced from Uniprot.org