Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
Purification: |
Affinity purification |
Concentration: |
Lot specific |
Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
KANSL1 |
Gene ID: |
284058 |
Uniprot ID: |
KANL1_HUMAN |
Immunogen Region: |
806-1105 |
Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 806-1105 of human KANSL1 (NP_056258.1). |
Immunogen Sequence: |
SSSSYLAATHHPPHSPLVRQ LSTSSDSPAPASSSSQVTAS TSQQPVRRRRGESSFDINNI VIPMSVAATTRVEKLQYKEI LTPSWREVDLQSLKGSPDEE NEEIEDLSDAAFAALHAKCE EMERARWLWTTSVPPQRRGS RSYRSSDGRTTPQLGSANPS TPQPASPDVSSSHSLSEYSH GQSPRSPISPELHSAPLTPV ARDTPRHLASEDTRCSTPEL GLDEQSVQPWERRTFPLAH |
Tissue Specificity | Expressed in the brain. |
Function | Non-catalytic component of the NSL histone acetyltransferase complex, a multiprotein complex that mediates histone H4 acetylation at 'Lys-5'- and 'Lys-8' (H4K5ac and H4K8ac) at transcription start sites and promotes transcription initiation. The NSL complex also acts as a regulator of gene expression in mitochondria. |
Protein Name | Kat8 Regulatory Nsl Complex Subunit 1Mll1/Mll Complex Subunit Kansl1Msl1 Homolog 1Hmsl1v1Nsl Complex Protein Nsl1Non-Specific Lethal 1 Homolog |
Database Links | Reactome: R-HSA-3214847Reactome: R-HSA-9772755 |
Cellular Localisation | NucleusChromosomeCentromereKinetochoreMitochondrion |
Alternative Antibody Names | Anti-Kat8 Regulatory Nsl Complex Subunit 1 antibodyAnti-Mll1/Mll Complex Subunit Kansl1 antibodyAnti-Msl1 Homolog 1 antibodyAnti-Hmsl1v1 antibodyAnti-Nsl Complex Protein Nsl1 antibodyAnti-Non-Specific Lethal 1 Homolog antibodyAnti-KANSL1 antibodyAnti-CENP-36 antibodyAnti-KIAA1267 antibodyAnti-MSL1V1 antibodyAnti-NSL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance