| Tissue Specificity | Specifically expressed in brain. |
| Function | Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH3 is brain-specific and appears to have an active role in certain neurons involved in motor coordination and memory. |
| Protein Name | Junctophilin-3Jp-3Junctophilin Type 3Trinucleotide Repeat-Containing Gene 22 Protein |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinEndoplasmic Reticulum MembraneSingle-Pass Type Iv Membrane ProteinLocalized Predominantly On The Plasma MembraneThe Transmembrane Domain Is Anchored In Endoplasmic Reticulum MembraneWhile The N-Terminal Part Associates With The Plasma Membrane |
| Alternative Antibody Names | Anti-Junctophilin-3 antibodyAnti-Jp-3 antibodyAnti-Junctophilin Type 3 antibodyAnti-Trinucleotide Repeat-Containing Gene 22 Protein antibodyAnti-JPH3 antibodyAnti-JP3 antibodyAnti-TNRC22 antibody |
Information sourced from Uniprot.org
