| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ITGA11 |
| Gene ID: | 22801 |
| Uniprot ID: | ITA11_HUMAN |
| Immunogen Region: | 940-1141 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 940-1141 of human ITGA11 (NP_001004439.1). |
| Immunogen Sequence: | KEDNVAPLRFHLKYEADVLF TRSSSLSHYEVKPNSSLERY DGIGPPFSCIFRIQNLGLFP IHGMMMKITIPIATRSGNRL LKLRDFLTDEANTSCNIWGN STEYRPTPVEEDLRRAPQLN HSNSDVVSINCNIRLVPNQE INFHLLGNLWLRSLKALKYK SMKIMVNAALQRQFHSPFIF REEDPSRQIVFEISKQEDWQ VP |
| Tissue Specificity | highest levels of expression in uterus and heart, intermediate levels in skeletal muscle and intermediate to low levels in pancreas, kidney and placenta. also found in brain, colon, lung, small intestine, stomach, testis, salivary glands, thyroid glands and prostate. Very low levels in peripheral blood lymphocytes, fetal brain and fetal liver. |
| Function | Integrin alpha-11/beta-1 is a receptor for collagen. |
| Protein Name | Integrin Alpha-11 |
| Database Links | Reactome: R-HSA-216083 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Integrin Alpha-11 antibodyAnti-ITGA11 antibodyAnti-MSTP018 antibody |
Information sourced from Uniprot.org