| Host: |
Rabbit |
| Applications: |
WB/IF/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Estradiol 17-beta-dehydrogenase 11 (71-120 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000ELISA 1:5000IF 1:100-300 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HSD17B11 |
| Gene ID: |
51170 |
| Uniprot ID: |
DHB11_HUMAN |
| Immunogen Region: |
71-120 aa |
| Specificity: |
17 Beta-HSD11 Polyclonal Antibody detects endogenous levels of 17 Beta-HSD11 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human DHRS8 at the amino acid range 71-120 |
| Function | Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma. |
| Protein Name | Estradiol 17-Beta-Dehydrogenase 1117-Beta-Hydroxysteroid Dehydrogenase 1117-Beta-Hsd 1117bhsd1117betahsd1117-Beta-Hydroxysteroid Dehydrogenase Xi17-Beta-Hsd Xi17betahsdxiCutaneous T-Cell Lymphoma-Associated Antigen Hd-Cl-03Ctcl-Associated Antigen Hd-Cl-03Dehydrogenase/Reductase Sdr Family Member 8Retinal Short-Chain Dehydrogenase/Reductase 2Retsdr2Short Chain Dehydrogenase/Reductase Family 16c Member 2 |
| Database Links | Reactome: R-HSA-193144 |
| Cellular Localisation | Endoplasmic ReticulumLipid DropletRedistributed From The Endoplasmic Reticulum To Lipids Droplets In The Cell Upon Induction Of Lipids Droplet Formation |
| Alternative Antibody Names | Anti-Estradiol 17-Beta-Dehydrogenase 11 antibodyAnti-17-Beta-Hydroxysteroid Dehydrogenase 11 antibodyAnti-17-Beta-Hsd 11 antibodyAnti-17bhsd11 antibodyAnti-17betahsd11 antibodyAnti-17-Beta-Hydroxysteroid Dehydrogenase Xi antibodyAnti-17-Beta-Hsd Xi antibodyAnti-17betahsdxi antibodyAnti-Cutaneous T-Cell Lymphoma-Associated Antigen Hd-Cl-03 antibodyAnti-Ctcl-Associated Antigen Hd-Cl-03 antibodyAnti-Dehydrogenase/Reductase Sdr Family Member 8 antibodyAnti-Retinal Short-Chain Dehydrogenase/Reductase 2 antibodyAnti-Retsdr2 antibodyAnti-Short Chain Dehydrogenase/Reductase Family 16c Member 2 antibodyAnti-HSD17B11 antibodyAnti-DHRS8 antibodyAnti-PAN1B antibodyAnti-SDR16C2 antibodyAnti-PSEC0029 antibodyAnti-UNQ207 antibodyAnti-PRO233 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
