| Tissue Specificity | Detected in liver and kidney. |
| Function | Serine protease that cleaves extracellular substrates, and contributes to the proteolytic processing of growth factors, such as HGF and MST1/HGFL. Plays a role in cell growth and maintenance of cell morphology. Plays a role in the proteolytic processing of ACE2. Mediates the proteolytic cleavage of urinary UMOD that is required for UMOD polymerization. |
| Protein Name | Serine Protease HepsinTransmembrane Protease Serine 1 Cleaved Into - Serine Protease Hepsin Non-Catalytic Chain - Serine Protease Hepsin Catalytic Chain |
| Database Links | Reactome: R-HSA-6806942Reactome: R-HSA-8852405 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinApical Cell Membrane |
| Alternative Antibody Names | Anti-Serine Protease Hepsin antibodyAnti-Transmembrane Protease Serine 1 Cleaved Into - Serine Protease Hepsin Non-Catalytic Chain - Serine Protease Hepsin Catalytic Chain antibodyAnti-HPN antibodyAnti-TMPRSS1 antibody |
Information sourced from Uniprot.org
