| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | GPR26 |
| Gene ID: | 2849 |
| Uniprot ID: | GPR26_HUMAN |
| Immunogen Region: | 150-250 aa |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human GPR26 (NP_703143.1). |
| Immunogen Sequence: | HQLYASCTLCSRRPDERLRF AVFTGAFHALSFLLSFVVLC CTYLKVLKVARFHCKRIDVI TMQTLVLLVDLHPSVRERCL EEQKRRRQRATKKISTFIGT F |
| Tissue Specificity | Highly expressed in the CNS, the highest expression is seen in the amygdala, hippocampus and thalamus. Weak expression is detected in testis. Down-regulated in glioblastoma. |
| Function | Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. |
| Protein Name | G-Protein Coupled Receptor 26 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-G-Protein Coupled Receptor 26 antibodyAnti-GPR26 antibody |
Information sourced from Uniprot.org