| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GPR22 |
| Gene ID: | 2845 |
| Uniprot ID: | GPR22_HUMAN |
| Immunogen Region: | 1-100 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GPR22 (NP_005286.2). |
| Immunogen Sequence: | MCFSPILEINMQSESNITVR DDIDDINTNMYQPLSYPLSF QVSLTGFLMLEIVLGLGSNL TVLVLYCMKSNLINSVSNII TMNLHVLDVIICVGCIPLTI |
| Tissue Specificity | High expression in adult and fetal heart tissue. Expressed in the brain, with enrichment in the accumbens, amygdala, cerebellum, cortex, and hippocampus regions. |
| Function | Orphan G-protein coupled receptor. Seems to act through a G(i)/G(o) mediated pathway. May be involved in ciliogenesis. |
| Protein Name | G-Protein Coupled Receptor 22 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-G-Protein Coupled Receptor 22 antibodyAnti-GPR22 antibody |
Information sourced from Uniprot.org