Immunofluorescence analysis of L929 cells using GBAS Rabbit polyclonal antibody (STJ119895) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.

Anti-GBAS antibody (1-50) (STJ119895)

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STJ119895
£112.50 - £524.50
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NIPSNAP2
Gene ID: 2631
Uniprot ID: NIPS2_HUMAN
Immunogen Region: 1-50
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-50 of human GBAS (NP_001474.1).
Immunogen Sequence: MAARVLRARGAAWAGGLLQR AAPCSLLPRLRTWTSSSNRS REDSWLKSLF
Tissue Specificity Widely expressed. Most abundant in heart and skeletal muscle.
Function Protein involved in mitophagy by facilitating recruitment of the autophagy machinery required for clearance of damaged mitochondria. Accumulates on the mitochondria surface in response to mitochondrial depolarization and acts as a 'eat me' signal by recruiting proteins involved in selective autophagy, such as autophagy receptors (CALCOCO2/NDP52, NBR1, SQSTM1/p62, TAX1BP1 and WDFY3/ALFY) and ATG8 family proteins (MAP1LC3A, MAP1LC3B, MAP1LC3C, GABARAP, GABARAPL1 and GABARAPL2).
Protein Name Protein Nipsnap Homolog 2
Nipsnap2
Glioblastoma-Amplified Sequence
Database Links Reactome: R-HSA-9013407
Reactome: R-HSA-9013409
Cellular Localisation Mitochondrion Matrix
Alternative Antibody Names Anti-Protein Nipsnap Homolog 2 antibody
Anti-Nipsnap2 antibody
Anti-Glioblastoma-Amplified Sequence antibody
Anti-NIPSNAP2 antibody
Anti-GBAS antibody

Information sourced from Uniprot.org

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