Tissue Specificity | Expressed in organs that contain secretory epithelial glands. Highly expressed in pancreas, skin, kidney and testis. Weakly expressed in prostate, ovary, intestine and colon. Also expressed in placenta and lung and fetal lung and fetal kidney. |
Function | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward HIV envelope glycoprotein gp120, EA2, MUC2, MUC1A and MUC5AC. Probably glycosylates fibronectin in vivo. Glycosylates FGF23. |
Protein Name | Polypeptide N-Acetylgalactosaminyltransferase 3Polypeptide Galnac Transferase 3Galnac-T3Pp-Gantase 3Protein-Udp Acetylgalactosaminyltransferase 3Udp-Galnac -Polypeptide N-Acetylgalactosaminyltransferase 3 |
Database Links | Reactome: R-HSA-190372Reactome: R-HSA-5083625Reactome: R-HSA-913709 |
Cellular Localisation | Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinResides Preferentially In The Trans And Medial Parts Of The Golgi Stack |
Alternative Antibody Names | Anti-Polypeptide N-Acetylgalactosaminyltransferase 3 antibodyAnti-Polypeptide Galnac Transferase 3 antibodyAnti-Galnac-T3 antibodyAnti-Pp-Gantase 3 antibodyAnti-Protein-Udp Acetylgalactosaminyltransferase 3 antibodyAnti-Udp-Galnac -Polypeptide N-Acetylgalactosaminyltransferase 3 antibodyAnti-GALNT3 antibody |
Information sourced from Uniprot.org