| Host: | Rabbit |
| Applications: | IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | IHC:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | FOSL2 |
| Gene ID: | 2355 |
| Uniprot ID: | FOSL2_HUMAN |
| Immunogen Region: | 201-300 aa |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 201-300 of human FOSL2/FRA2 (NP_005244.1). |
| Immunogen Sequence: | PPAPGLQPMRSGGGSVGAVV VKQEPLEEDSPSSSSAGLDK AQRSVIKPISIAGGFYGEEP LHTPIVVTSTPAVTPGTSNL VFTYPSVLEQESPASPSESC |
| Function | Controls osteoclast survival and size. As a dimer with JUN, activates LIF transcription. Activates CEBPB transcription in PGE2-activated osteoblasts. |
| Protein Name | Fos-Related Antigen 2Fra-2 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Fos-Related Antigen 2 antibodyAnti-Fra-2 antibodyAnti-FOSL2 antibodyAnti-FRA2 antibody |
Information sourced from Uniprot.org