Tissue Specificity | Expressed in the secondary lymphoid organs, spleen and lymph node. Expression is limited to the mature B-cell lines. Highly expressed in CD19 and within the mantle zones of the tonsil tissue. Isoform 2 is expressed in the spleen, peripheral blood and bone marrow. Isoform 2 and isoform 4 are expressed in B-cell lines. Preferentially expressed in memory B-cells (at protein level). |
Post Translational Modifications | Isoform 2 is N- and O-glycosylated, and phosphorylated. |
Function | May have an regulatory role in normal and neoplastic B cell development. |
Protein Name | Fc Receptor-Like Protein 2Fcr-Like Protein 2Fcrl2Fc Receptor Homolog 2Fcrh2Ifgp Family Protein 4Immunoglobulin Receptor Translocation-Associated Protein 4Sh2 Domain-Containing Phosphatase Anchor Protein 1Cd Antigen Cd307b |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Fc Receptor-Like Protein 2 antibodyAnti-Fcr-Like Protein 2 antibodyAnti-Fcrl2 antibodyAnti-Fc Receptor Homolog 2 antibodyAnti-Fcrh2 antibodyAnti-Ifgp Family Protein 4 antibodyAnti-Immunoglobulin Receptor Translocation-Associated Protein 4 antibodyAnti-Sh2 Domain-Containing Phosphatase Anchor Protein 1 antibodyAnti-Cd Antigen Cd307b antibodyAnti-FCRL2 antibodyAnti-FCRH2 antibodyAnti-IFGP4 antibodyAnti-IRTA4 antibodyAnti-SPAP1 antibodyAnti-UNQ9236 antibodyAnti-PRO31998 antibody |
Information sourced from Uniprot.org