• Western blot analysis of extracts of mouse brain, using FBXW4 antibody (STJ110448) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
  • Western blot analysis of extracts of mouse brain, using FBXW4 antibody (STJ110448) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-FBXW4 antibody (143-412) (STJ110448)

SKU:
STJ110448

£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FBXW4
Gene ID: 6468
Uniprot ID: FBXW4_HUMAN
Immunogen Region: 143-412
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 143-412 of human FBXW4 (NP_071322.1).
Immunogen Sequence: QFRPDGASLNRRPLGVFAGH DEDVCHFVLANSHIVSAGGD GKIGIHKIHSTFTVKYSAHE QEVNCVDCKGGIIVSGSRDR TAKVWPLASGRLGQCLHTIQ TEDRVWSIAISPLLSSFVTG TACCGHFSPLRIWDLNSGQL MTHLGSDFPPGAGVLDVMYE SPFTLLSCGYDTYVRYWDLR TSVRKCVMEWEEPHDSTLYC LQTDGNHLLATGSSYYGVVR LWDRRQRACLHAFPLTSTP
Tissue Specificity Expressed in brain, kidney, lung and liver.
Function Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling.
Protein Name F-Box/Wd Repeat-Containing Protein 4
Dactylin
F-Box And Wd-40 Domain-Containing Protein 4
Database Links Reactome: R-HSA-390471
Reactome: R-HSA-8951664
Reactome: R-HSA-983168
Alternative Antibody Names Anti-F-Box/Wd Repeat-Containing Protein 4 antibody
Anti-Dactylin antibody
Anti-F-Box And Wd-40 Domain-Containing Protein 4 antibody
Anti-FBXW4 antibody
Anti-FBW4 antibody
Anti-SHFM3 antibody

Information sourced from Uniprot.org

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