| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FASTKD5 |
| Gene ID: | 60493 |
| Uniprot ID: | FAKD5_HUMAN |
| Immunogen Region: | 495-764 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 495-764 of human FASTKD5 (NP_068598.1). |
| Immunogen Sequence: | SPGFVRLAQERTKFDLLKEL YTLDGTVGIECPDYRGNRLS THLQQEGSELLWYLAEKDMN SKPEFLETVFLLETMLGGPQ YVKHHMILPHTRSSDLEVQL DVNLKPLPFNREATPAENVA KLRLEHVGVSLTDDLMNKLL KGKARGHFQGKTESEPGQQP MELENKAAVPLGGFLCNVAD KSGAMEMAGLCPAACMQTPR MKLAVQFTNRNQYCYGSRDL LGLHNMKRRQLARLGYRVV |
| Tissue Specificity | Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart, smooth muscle, liver and thyroid. |
| Function | Plays an important role in the processing of non-canonical mitochondrial mRNA precursors. |
| Protein Name | Fast Kinase Domain-Containing Protein 5 - Mitochondrial |
| Database Links | Reactome: R-HSA-9837092 |
| Cellular Localisation | Mitochondrion MatrixMitochondrion NucleoidLocalizes To Mitochondrial Rna Granules Found In Close Proximity To The Mitochondrial Nucleoids |
| Alternative Antibody Names | Anti-Fast Kinase Domain-Containing Protein 5 - Mitochondrial antibodyAnti-FASTKD5 antibodyAnti-KIAA1792 antibody |
Information sourced from Uniprot.org