| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | FASTKD3 |
| Gene ID: | 79072 |
| Uniprot ID: | FAKD3_HUMAN |
| Immunogen Region: | 1-220 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human FASTKD3 (NP_076996.2). |
| Immunogen Sequence: | MALITLRKNLYRLSDFQMHR ALAALKNKPLNHVHKVVKER LCPWLCSRQPEPFGVKFHHA HCKKFHSKNGNDLHPLGGPV FSQVSDCDRLEQNVKNEESQ MFYRRLSNLTSSEEVLSFIS TMETLPDTMAAGALQRICEV EKKDGDQGLPKEILENSIFQ ALCFQFEKEPSQLSNTSLVT ALQALILLHVDPQSSLLLNL VAECQNRLRKGGMEVRNLCI |
| Tissue Specificity | Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in liver and thyroid. |
| Function | Required for normal mitochondrial respiration. Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6. Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity. |
| Protein Name | Fast Kinase Domain-Containing Protein 3 - Mitochondrial |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Fast Kinase Domain-Containing Protein 3 - Mitochondrial antibodyAnti-FASTKD3 antibody |
Information sourced from Uniprot.org