Tissue Specificity | Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart, smooth muscle and thyroid. |
Function | Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation. May play a role in mitochondrial apoptosis. |
Protein Name | Fast Kinase Domain-Containing Protein 2 - Mitochondrial |
Database Links | Reactome: R-HSA-9837092 |
Cellular Localisation | Mitochondrion MatrixMitochondrion NucleoidLocalizes To Mitochondrial Rna Granules Found In Close Proximity To The Mitochondrial Nucleoids |
Alternative Antibody Names | Anti-Fast Kinase Domain-Containing Protein 2 - Mitochondrial antibodyAnti-FASTKD2 antibodyAnti-KIAA0971 antibody |
Information sourced from Uniprot.org