| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TENT5C |
| Gene ID: | 54855 |
| Uniprot ID: | TET5C_HUMAN |
| Immunogen Region: | 1-110 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human FAM46C (NP_060179.2). |
| Immunogen Sequence: | MAEESSCTRDCMSFSVLNWD QVSRLHEVLTEVVPIHGRGN FPTLEITLKDIVQTVRSRLE EAGIKVHDVRLNGSAAGHVL VKDNGLGCKDLDLIFHVALP TEAEFQLVRD |
| Function | Catalyzes the transfer of one adenosine molecule from an ATP to an mRNA poly(A) tail bearing a 3'-OH terminal group and enhances mRNA stability and gene expression. Can also elongate RNA oligos ending with uridine molecule, provided that the sequence is adenosine-rich. Mainly targets mRNAs encoding endoplasmic reticulum-targeted protein. (Microbial infection) Seems to enhance replication of some viruses, including yellow fever virus, in response to type I interferon. |
| Protein Name | Terminal Nucleotidyltransferase 5cNon-Canonical Poly(A Polymerase Fam46c |
| Cellular Localisation | NucleusCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeRecruited Into The Centrosome Through Its Interaction With Plk4 |
| Alternative Antibody Names | Anti-Terminal Nucleotidyltransferase 5c antibodyAnti-Non-Canonical Poly(A Polymerase Fam46c antibodyAnti-TENT5C antibodyAnti-FAM46C antibody |
Information sourced from Uniprot.org