• Western blot analysis of extracts of mouse kidney, using EVC antibody (STJ114509) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-EVC antibody (743-992) (STJ114509)

SKU:
STJ114509

£169.50 - £449.50
Shipping:
Free Shipping
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-EVC (743-992) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:3000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: EVC
Gene ID: 2121
Uniprot ID: EVC_HUMAN
Immunogen Region: 743-992
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 743-992 of human EVC (NP_714928.1).
Immunogen Sequence: AIGQALLVHARNAATKSRAK DRDDFKRTLMEAAVESVYVT SAGVSRLVQAYYQQIGRIME DHEERKLQHLKTLQGERMEN YKLRKKQELSNPSSGSRTAG GAHETSQAVHQRMLSQQKRF LAQFPVHQQMRLHAQQQQAG VMDLLEAQLETQLQEAEQNF ISELAALARVPLAESKLLPA KRGLLEKPLRTKRKKPLPQE RGDLGVPNNEDLASGDQTSG SLSSKRLSQQESEAGDSGN
Tissue Specificity Found in the developing vertebral bodies, ribs, upper and lower limbs, heart, kidney, lung.
Function Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Involved in endochondral growth and skeletal development.
Protein Name Evc Complex Member Evc
Dwf-1
Ellis-Van Creveld Syndrome Protein
Database Links Reactome: R-HSA-5632684
Reactome: R-HSA-5635838
Cellular Localisation Cell Membrane
Single-Pass Membrane Protein
Cytoplasm
Cytoskeleton
Cilium Basal Body
Cell Projection
Cilium
Cilium Membrane
Evc2 Is Required For The Localization Of Evc At The Base Of Primary Cilia
The Evc Complex Localizes At The Base Of Cilia In The Evc Zone Of Primary Cilia In A Efcab7-Dependent Manner
Alternative Antibody Names Anti-Evc Complex Member Evc antibody
Anti-Dwf-1 antibody
Anti-Ellis-Van Creveld Syndrome Protein antibody
Anti-EVC antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance