| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | ESM1 |
| Gene ID: | 11082 |
| Uniprot ID: | ESM1_HUMAN |
| Immunogen Region: | 20-184 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-184 of human ESM1 (NP_008967.1). |
| Immunogen Sequence: | WSNNYAVDCPQHCDSSECKS SPRCKRTVLDDCGCCRVCAA GRGETCYRTVSGMDGMKCGP GLRCQPSNGEDPFGEEFGIC KDCPYGTFGMDCRETCNCQS GICDRGTGKCLKFPFFQYSV TKSSNRFVSLTEHDMASGDG NIVREEVVKENAAGSPVMRK WLNPR |
| Tissue Specificity | Expressed in lung, on the vascular capillary network within alveolar walls, and also at lower level in kidney. |
| Post Translational Modifications | May contain intrachain disulfide bonds. O-glycosylated.contains chondroitin sulfate and dermatan sulfate. |
| Function | Involved in angiogenesis.promotes angiogenic sprouting. May have potent implications in lung endothelial cell-leukocyte interactions. |
| Protein Name | Endothelial Cell-Specific Molecule 1Esm-1 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Endothelial Cell-Specific Molecule 1 antibodyAnti-Esm-1 antibodyAnti-ESM1 antibody |
Information sourced from Uniprot.org