| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Endogenous retrovirus group K member 24 Env polyprotein (64-114 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ERVK-24 |
| Uniprot ID: |
ENK24_HUMAN |
| Immunogen Region: |
64-114 aa |
| Specificity: |
This antibody detects endogenous levels of human ENK11 |
| Immunogen: |
Synthesized peptide derived from the human ENK11 at the amino acid range 64-114 |
| Post Translational Modifications | Specific enzymatic cleavages in vivo yield the mature SU and TM proteins. |
| Function | Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. SU mediates receptor recognition. TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane. |
| Protein Name | Endogenous Retrovirus Group K Member 24 Env PolyproteinEnvelope PolyproteinHerv-K101 Envelope ProteinHerv-K_22q11.21 Provirus Ancestral Env Polyprotein Cleaved Into - Surface ProteinSu - Transmembrane ProteinTm |
| Cellular Localisation | Transmembrane Protein: Cell MembraneSingle-Pass Type I Membrane ProteinSurface Protein: Cell MembranePeripheral Membrane ProteinThe Surface Protein Is Not Anchored To The MembraneBut Localizes To The Extracellular Surface Through Its Binding To TmEndogenous Retrovirus Group K Member 24 Env Polyprotein: Virion |
| Alternative Antibody Names | Anti-Endogenous Retrovirus Group K Member 24 Env Polyprotein antibodyAnti-Envelope Polyprotein antibodyAnti-Herv-K101 Envelope Protein antibodyAnti-Herv-K_22q11.21 Provirus Ancestral Env Polyprotein Cleaved Into - Surface Protein antibodyAnti-Su - Transmembrane Protein antibodyAnti-Tm antibodyAnti-ERVK-24 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
