| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Transcription Factor Coe2 is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Purification: | Antigen affinity purification |
| Concentration: | 1.68 mg/mL |
| Dilution Range: | WB 1:500-1:2000 |
| Storage Instruction: | Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Gene Symbol: | EBF2 |
| Gene ID: | 64641 |
| Uniprot ID: | COE2_HUMAN |
| Immunogen: | Synthetic peptide of human EBF2 |
| Function | Transcription factor that, in osteoblasts, activates the decoy receptor for RANKL, TNFRSF11B, which in turn regulates osteoclast differentiation. Acts in synergy with the Wnt-responsive LEF1/CTNNB1 pathway. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. |
| Protein Name | Transcription Factor Coe2Early B-Cell Factor 2Ebf-2 |
| Database Links | Reactome: R-HSA-9844594 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Coe2 antibodyAnti-Early B-Cell Factor 2 antibodyAnti-Ebf-2 antibodyAnti-EBF2 antibodyAnti-COE2 antibody |
Information sourced from Uniprot.org