| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
DNAAF4 |
| Gene ID: |
161582 |
| Uniprot ID: |
DAAF4_HUMAN |
| Immunogen Region: |
1-240 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human DYX1C1 (NP_001028732.1). |
| Immunogen Sequence: |
MPLQVSDYSWQQTKTAVFLS LPLKGVCVRDTDVFCTENYL KVNFPPFLFEAFLYAPIDDE SSKAKIGNDTIVFTLYKKEA AMWETLSVTGVDKEMMQRIR EKSILQAQERAKEATEAKAA AKREDQKYALSVMMKIEEEE RKKIEDMKENERIKATKALE AWKEYQRKAEEQKKIQREEK LCQKEKQIKEERKKIKYKSL TRNLASRNLAPKGRNSENIF TEKLKEDSIPAPRSVGSIK |
| Tissue Specificity | Expressed in several tissues, including brain, lung, kidney and testis. In brain localizes to a fraction of cortical neurons and white matter glial cells. |
| Function | Axonemal dynein assembly factor required for ciliary motility. Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity. |
| Protein Name | Dynein Axonemal Assembly Factor 4Dyslexia Susceptibility 1 Candidate Gene 1 Protein |
| Cellular Localisation | NucleusCytoplasmDynein Axonemal ParticleCell ProjectionNeuron Projection |
| Alternative Antibody Names | Anti-Dynein Axonemal Assembly Factor 4 antibodyAnti-Dyslexia Susceptibility 1 Candidate Gene 1 Protein antibodyAnti-DNAAF4 antibodyAnti-DYX1C1 antibodyAnti-EKN1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
