| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DNAJC24 (2-149) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DNAJC24 |
| Gene ID: |
120526 |
| Uniprot ID: |
DJC24_HUMAN |
| Immunogen Region: |
2-149 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 2-149 of human DNAJC24 (NP_859057.4). |
| Immunogen Sequence: |
MAVEQMPKKDWYSILGADPS ANISDLKQKYQKLILMYHPD KQSTDVPAGTVEECVQKFIE IDQAWKILGNEETKREYDLQ RCEDDLRNVGPVDAQVYLEE MSWNEGDHSFYLSCRCGGKY SVSKDEAEEVSLISCDTCSL IIELLHYN |
| Function | Stimulates the ATPase activity of several Hsp70-type chaperones. This ability is enhanced by iron-binding. The iron-bound form is redox-active and can function as electron carrier. Plays a role in the diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta). |
| Protein Name | Dnaj Homolog Subfamily C Member 24Csl-Type Zinc Finger-Containing Protein 3Diphthamide Biosynthesis Protein 4 |
| Database Links | Reactome: R-HSA-5358493 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Dnaj Homolog Subfamily C Member 24 antibodyAnti-Csl-Type Zinc Finger-Containing Protein 3 antibodyAnti-Diphthamide Biosynthesis Protein 4 antibodyAnti-DNAJC24 antibodyAnti-DPH4 antibodyAnti-ZCSL3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
