Anti-Cytochrome P450 2E1 antibody [SRM] (STJ11106876)

SKU:
STJ11106876
£129.50 - £574.50
Processing The item has been added

Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : SRM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:2000-1:20000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Gene Symbol: CYP2E1
Gene ID: 1571
Uniprot ID: CP2E1_HUMAN
Specificity: Recombinant protein of human Cytochrome P450 2E1 (CYP2E1).
Function A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics (Probable).
Protein Name Cytochrome P450 2e1
4-Nitrophenol 2-Hydroxylase
Cypiie1
Cytochrome P450-J
Database Links Reactome: R-HSA-211981
Reactome: R-HSA-211999
Reactome: R-HSA-9027307
Reactome: R-HSA-9749641
Reactome: R-HSA-9753281
Cellular Localisation Endoplasmic Reticulum Membrane
Peripheral Membrane Protein
Microsome Membrane
Mitochondrion Inner Membrane
Post-Translationally Targeted To Mitochondria
Tomm70 Is Required For The Translocation Across The Mitochondrial Outer Membrane
After Translocation Into The Matrix
Associates With The Inner Membrane As A Membrane Extrinsic Protein
Alternative Antibody Names Anti-Cytochrome P450 2e1 antibody
Anti-4-Nitrophenol 2-Hydroxylase antibody
Anti-Cypiie1 antibody
Anti-Cytochrome P450-J antibody
Anti-CYP2E1 antibody
Anti-CYP2E antibody

Information sourced from Uniprot.org