| Host: | Mouse |
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-CRP is suitable for use in ELISA research applications. |
| Clonality : | Monoclonal |
| Clone ID : | 6407 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Purification: | Purity accurate to greater than or equal to 95% |
| Concentration: | 5.0 mg/ml (+/-10 %) |
| Storage Instruction: | 24 months from manufacturing at 2°C. Temperature analysis:-70 °C, 21 days N/D-20 °C, 21 days OK +4 °C, 21 days OK +30 °C, 21 OK +35 °C, 21 days OK +45 °C, 7 days OK. Shelf life stability testing at 2–8 °C in the product buffer. |
| Association Rate Constant: | 8.9 x 105 1/Ms |
| Determination Method: | SPR analysis (ProteOn XPR36) |
| Immunoreactivity: | 80–120 % compared to the reference sample in an FIA test |
| Gene Symbol: | CRP |
| Gene ID: | 1401 |
| Uniprot ID: | CRP_HUMAN |
| Immunogen: | human C-reactive protein (CRP) , binding is Ca2+ independent |
| Tissue Specificity | Found in plasma. |
| Function | Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. |
| Protein Name | C-Reactive Protein Cleaved Into - C-Reactive Protein(1-205 |
| Database Links | Reactome: R-HSA-173623 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-Reactive Protein Cleaved Into - C-Reactive Protein(1-205 antibodyAnti-CRP antibodyAnti-PTX1 antibody |
Information sourced from Uniprot.org