Anti-COX7A1 antibody (1-79) (STJ116921)

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STJ116921
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Host: Rabbit
Applications: WB/IHC-P/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:100-1:500
IHC-P:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: COX7A1
Gene ID: 1346
Uniprot ID: CX7A1_HUMAN
Immunogen Region: 1-79
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-79 of human COX7A1 (NP_001855.1).
Immunogen Sequence: MQALRVSQALIRSFSSTARN RFQNRVREKQKLFQEDNDIP LYLKGGIVDNILYRVTMTLC LGGTVYSLYSLGWASFPRN
Function Component of the mitochondrial respiratory complex IV (CIV, also named cytochrome c oxidase complex), the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The CIV complex is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Acts as an assembly factor that specifically drives the homodimerization of CIV complexes, mediating the formation of mitochondrial respiratory supercomplexes (respirasomes) containing two CIV: supercomplxes with two molecules of CIV show improved activity. Despite being highly expressed in brown adipose tissue, not required for thermogenesis.
Protein Name Cytochrome C Oxidase Subunit 7a1 - Mitochondrial
Cytochrome C Oxidase Subunit Viia-Heart
Cytochrome C Oxidase Subunit Viia-H
Cytochrome C Oxidase Subunit Viia-Muscle
Cytochrome C Oxidase Subunit Viia-M
Database Links Reactome: R-HSA-5628897
Reactome: R-HSA-611105
Reactome: R-HSA-9707564
Reactome: R-HSA-9844594
Reactome: R-HSA-9864848
Cellular Localisation Mitochondrion Inner Membrane
Single-Pass Membrane Protein
Alternative Antibody Names Anti-Cytochrome C Oxidase Subunit 7a1 - Mitochondrial antibody
Anti-Cytochrome C Oxidase Subunit Viia-Heart antibody
Anti-Cytochrome C Oxidase Subunit Viia-H antibody
Anti-Cytochrome C Oxidase Subunit Viia-Muscle antibody
Anti-Cytochrome C Oxidase Subunit Viia-M antibody
Anti-COX7A1 antibody
Anti-COX7AH antibody

Information sourced from Uniprot.org