| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | COLGALT1 |
| Gene ID: | 79709 |
| Uniprot ID: | GT251_HUMAN |
| Immunogen Region: | 30-230 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-230 of human COLGALT1 (NP_078932.2). |
| Immunogen Sequence: | APPGADAYFPEERWSPESPL QAPRVLIALLARNAAHALPT TLGALERLRHPRERTALWVA TDHNMDNTSTVLREWLVAVK SLYHSVEWRPAEEPRSYPDE EGPKHWSDSRYEHVMKLRQA ALKSARDMWADYILFVDADN LILNPDTLSLLIAENKTVVA PMLDSRAAYSNFWCGMTSQG YYKRTPAYIPIRKRDRRGCF A |
| Tissue Specificity | Ubiquitous with higher levels in placenta, heart, lung and spleen. |
| Post Translational Modifications | N-glycosylated. |
| Function | Beta-galactosyltransferase that transfers beta-galactose to hydroxylysine residues of type I collagen. By acting on collagen glycosylation, facilitates the formation of collagen triple helix. Also involved in the biosynthesis of collagen type IV. |
| Protein Name | Procollagen Galactosyltransferase 1Collagen Beta(1-Ogalactosyltransferase 1Colgalt 1Glycosyltransferase 25 Family Member 1Hydroxylysine Galactosyltransferase 1 |
| Database Links | Reactome: R-HSA-1650814 |
| Cellular Localisation | Endoplasmic Reticulum LumenColocalized With Plod3 And Mannose Binding Lectin/Mbl2 |
| Alternative Antibody Names | Anti-Procollagen Galactosyltransferase 1 antibodyAnti-Collagen Beta(1-Ogalactosyltransferase 1 antibodyAnti-Colgalt 1 antibodyAnti-Glycosyltransferase 25 Family Member 1 antibodyAnti-Hydroxylysine Galactosyltransferase 1 antibodyAnti-COLGALT1 antibodyAnti-GLT25D1 antibodyAnti-PSEC0241 antibody |
Information sourced from Uniprot.org