| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CNTROB |
| Gene ID: | 116840 |
| Uniprot ID: | CNTRB_HUMAN |
| Immunogen Region: | 604-903 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 604-903 of human CNTROB (NP_444279.2). |
| Immunogen Sequence: | PMAVALKPVLQQSREARDEL PGAPPVLCSSSSDLSLLLGP SFQSQHSFQPLEPKPDLTSS TAGAFSALGAFHPDHRAERP FPEEDPGPDGEGLLKQGLPP AQLEGLKNFLHQLLETVPQN NENPSVDLLPPKSGPLTVPS WEEAPQVPRIPPPVHKTKVP LAMASSLFRVPEPPSSHSQG SGPSSGSPERGGDGLTFPRQ LMEVSQLLRLYQARGWGALP AEDLLLYLKRLEHSGTDGR |
| Tissue Specificity | Widely expressed (at protein level). Highly expressed in testis. Also expressed in spleen, thymus, prostate, small intestine, colon and peripheral blood leukocytes. |
| Function | Required for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis. |
| Protein Name | Centrobin Centrosomal Brca2-Interacting Protein Lyst-Interacting Protein 8 |
| Cellular Localisation | Cytoplasm Cytoskeleton Microtubule Organizing Center Centrosome Centriole Centriole-Associated Asymmetrically Localizes To The Daughter Centriole |
| Alternative Antibody Names | Anti-Centrobin antibody Anti-Centrosomal Brca2-Interacting Protein antibody Anti-Lyst-Interacting Protein 8 antibody Anti-CNTROB antibody Anti-LIP8 antibody Anti-PP1221 antibody |
Information sourced from Uniprot.org