• Western blot analysis of extracts of SW620 cells, using CNTROB antibody (STJ110576) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-CNTROB antibody (604-903) (STJ110576)

SKU:
STJ110576

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CNTROB (604-903) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CNTROB
Gene ID: 116840
Uniprot ID: CNTRB_HUMAN
Immunogen Region: 604-903
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 604-903 of human CNTROB (NP_444279.2).
Immunogen Sequence: PMAVALKPVLQQSREARDEL PGAPPVLCSSSSDLSLLLGP SFQSQHSFQPLEPKPDLTSS TAGAFSALGAFHPDHRAERP FPEEDPGPDGEGLLKQGLPP AQLEGLKNFLHQLLETVPQN NENPSVDLLPPKSGPLTVPS WEEAPQVPRIPPPVHKTKVP LAMASSLFRVPEPPSSHSQG SGPSSGSPERGGDGLTFPRQ LMEVSQLLRLYQARGWGALP AEDLLLYLKRLEHSGTDGR
Tissue Specificity Widely expressed (at protein level). Highly expressed in testis. Also expressed in spleen, thymus, prostate, small intestine, colon and peripheral blood leukocytes.
Function Required for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis.
Protein Name Centrobin
Centrosomal Brca2-Interacting Protein
Lyst-Interacting Protein 8
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Centriole
Centriole-Associated
Asymmetrically Localizes To The Daughter Centriole
Alternative Antibody Names Anti-Centrobin antibody
Anti-Centrosomal Brca2-Interacting Protein antibody
Anti-Lyst-Interacting Protein 8 antibody
Anti-CNTROB antibody
Anti-LIP8 antibody
Anti-PP1221 antibody

Information sourced from Uniprot.org

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